Speciality and Domain

• Environmental and Occupational Health
• Sampling and analysis of air pollutants in the general and occupational environment
• Sampling, analysis, and exposure assessment of environmental trace toxics
• Health risk assessment and management of toxic chemicals
• Air pollution and control

Course

• Health Risk Assessment of Environmental Toxics
• Characterization of Air Pollutants
• Sampling and Analysis of Air Pollutant
• Introduction to Environmental Endocrine
• Industrial Hygiene and Environmental Health
• Advanced Exposure Assessment for workplace
• Public Health

Education

• Ph.D, Graduate Institute of Environmental Engineering, National Taiwan University

Experience

• Director, Office of Academic Integrity
• National Cheng Kung University, The Secretary General
• National Cheng Kung University, Center of Environmental Protection,Safety and Hygiene,Director
• Distinguished Professor, Department of environmental and Occupational Health, National Cheng Kung University
• President of Taiwan Society of Indoor Environmental Quality
• Department of Environmental and Occupational Health, College of Medicine, National Cheng Kung University Professor
• National Cheng Kung University College of Medicine.
• Research Center of Environmental Trace Toxic Substances, National Cheng Kung University Director
• Department of Environmental and Occupational Health, College of Medicine, National Cheng Kung University Associate professor
• Distinguished Professor, Department of environmental and Occupational Health, National Cheng Kung University
• Department of Environmental and Occupational Health, College of Medicine, National Cheng Kung University Lecturer
• Environmental Protection Administration Government of the Republic of China Section Chief
• Environmental Protection Bureau, Department of Health Section Chief
   

Publication

Papers

1. Wei-Hsiang Chang, Pei-Hsuan Chen, Samuel Herianto, Hsiu-Ling Chen, Ching-Chang Lee* (corresponding author), Aggregating exposures and toxicity equivalence approach into an integrated probabilistic dietary risk assessment for perchlorate, nitrate, and thiocyanate: Results from the National food monitoring study and National Food Consumption Database, Environmental Research, FEB, 2022, (Already accepted, SCI IF=6.498, rank=16/203=7.88% in Public, Environmental & Occupational Health, JCR 2020)

2. Lee, Ching-Chang; Wu, Yi-Yun; Chen, Colin S.; Tien, Chien-Jung, Spatiotemporal distribution and risk assessment of short-chain chlorinated paraffins in 30 major rivers in Taiwan, SCIENCE OF THE TOTAL ENVIRONMENT, Volume 806(4),150969,  FEB 1 ,2022,( SCI IF=7.963, rank=25/274=9.1% in Environmental Sciences, JCR 2020)

3. Lee, Ching-Chang; Chang, Wei-Hsiung; Hung, Chung-Feng; Chen, Hsiu-Ling, Fish consumption is an indicator of exposure to non-dioxin like polychlorinated biphenyls in cumulative risk assessments based on a probabilistic and sensitive approach, ENVIRONMENTAL POLLUTION, Volume268(B)115732, JAN 1,2021. (SCI IF=8.071, rank=23/274=8.4% in ENVIRONMENTAL SCIENCES, JCR 2020)

4. Liu, Pei-Wen; Li, Chung-, I; Huang, Kuo-Ching; Liu, Chiang-Shin; Chen, Hsiu-Lin; Lee, Ching-Chang; Chiou, Yuan-Yow; Chen, Rong-Jane,3-MCPD and glycidol coexposure induces systemic toxicity and synergistic nephrotoxicity via NLRP3 inflammasome activation, necroptosis, and autophagic cell death, . Journal of hazardous materials, 405,124241, MAR 5 2021 (SCI IF=10.588, rank=10/274=3.6% in Environmental Sciences, JCR 2020).

5. Wu-Ting Lin, Chung-Yu Chen, Ching-Chang Lee* (corresponding author), Cheng-Chen Chen* and Shih-Chi Lo, Air Phthalate Emitted from Flooring Building Material by the Micro-Chamber Method: Two-Stage Emission Evaluation and Comparison, Toxics, Volume  9(9),216 ,September, 2021 (SCI IF=4.146, rank=30/93=32.3% in Toxicology, JCR 2020)

6. Ching-Chang Lee, Colin S.Chen, Zi-Xuan Wang, Chien-Jung Tien, Polycyclic aromatic hydrocarbons in 30 river ecosystems, Taiwan: Sources, and ecological and human health risks, Science of the Total Environment. Volume795, 148867, NOV 15, 2021 (Already accepted,( SCI IF=7.963, rank=25/274=9.1% in Environmental Sciences, JCR 2020)

7. Wei-Hsiang Chang, Samuel Herianto, Ching-Chang Lee, Hsin Hung, and Hsiu-Ling Chen, The Effects of Phthalate Ester Exposure on Human Health: A Review, Science of the Total Environment, Volume 786, 147371 , 10 September 2021 ( SCI IF=7.963, rank=25/274=9.1% in Environmental Sciences, JCR 2020)

8. Po-Chin Huang, Pao-Lin Kuo, Wei-Hsiang Chang, Shu-Fang Shih, Wan-Ting Chang, Ching-Chang Lee (corresponding author), Prenatal Phthalates Exposure and Cord Thyroid Hormones: A Birth Cohort Study in Southern Taiwan, International Journal of Environmental Research and Public Health, 18(8), 4323, April 2021 (SCI IF=3.39, rank=68/203=33.5% in PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH, JCR 2020)

9. Ching-Chang Lee; Yi-Hsin Lin; Wen-Che Hou; Meng-Han Li; Jung-Wei Chang, Exposure to ZnO/TiO2 Nanoparticles Affects Health Outcomes in Cosmetics Salesclerks, International Journal of Environmental Research and Public Health 17(17):6088, Sep 2020 (SCI IF=2.849, rank=32/171=18.71% in PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH, JCR 2019).

10. Wei-Hsiang Chang, Hsiu-Ling Chen, Ching-Chang Lee (corresponding author), Dietary exposure assessment to perchlorate in the Taiwanese population: A risk assessment based on the probabilistic approach. Environmental Pollution, Volume 267, Pages 115486, Auguest 2020 (SCI IF=6.792, rank=21/265=7.92% in Environmental Sciences, JCR 2019).

11. Ching-Chang Lee, Wei-Hsiang Chang, Hsin-Tang Lin, Jung-Wei Chang, Spatiotemporal Patterns of Polychlorinated Dibenzo-p-dioxins and Dibenzofurans and Dioxin-like Polychlorinated Biphenyls in Foodstuffs in Air Quality Regions in Taiwan, Journal of Food and Drug Analysis, Volume 28, Pages 375-398, July 2020 (SCI IF=4.727, rank=13/139=9.35% in Food Science and Technology, JCR 2019).

12. Ching-Chang Lee, Chia-Yi Hsieh, Colin S.Chen, Chien-Jung Tien. Emergent contaminants in sediments and fishes from the Tamsui River (Taiwan): Their spatial-temporal distribution and risk to aquatic ecosystems and human health. Environmental Pollution, 258, 113733, March 2020. (SCI IF=5.714, rank=25/251=9.96% in Environmental Sciences, JCR 2018).

13. Ching-Chang Lee, Ying Shen, Chun-Wei Hsu, Jer-Pei Fong, Shi-Nian Uang, Jung-Wei Chang. Reduced adiponectin:leptin ratio associated with inhalation exposure to vinyl chloride monomer. Science of the Total Environment, 12:135488, Nov 2019. (SCI IF=5.589, rank=27/251=10.7% in Environmental Sciences, JCR 2018).

14. Ching-Chang Lee, Wei-Hsiang Chang, Hsiu-Ling Chen. Dietary exposure and risk assessment of exposure to hexabromocyclododecanes in a Taiwan population. Environmental Pollution, 249:728-734, Jun 2019. (SCI IF=5.714, rank=25/251=9.96% in Environmental Sciences, JCR 2018).

15. Wei-Hsiang Chang, Yuh-Shyan Tsai, Jia-YuWang, Hsiu-Ling Chen, Wen-HorngYang, Ching-Chang Lee (corresponding author). Sex hormones and oxidative stress mediated phthalate-induced effects in prostatic enlargement. Environment International, 126:184-192, May 2019. (SCI IF=7.943, rank=8/251=3.19% in Environmental Science, JCR 2018).

16. Wei-Hsiang Chang, Shou-Chun Liu, Hsiu-Ling Chen, Ching-Chang Lee (corresponding author), Dietary intake of 4-nonylphenol and bisphenol A in Taiwanese population: Integrated risk assessment based on probabilistic and sensitive approach, Environmental Pollution, 244, 143-152, Jan 2019. (SCI IF=5.714, rank=25/251=9.96% in Environmental Sciences, JCR 2018).

17. Kun-Chih Huang, Yaw-Shyan Tsay, Fang-Ming Lin, Ching-Chang Lee (equally contribution with corresponding author), Jung-Wei Chang (corresponding author), Efficiency and performance tests of the sorptive building materials that reduce indoor formaldehyde concentrations, PLOS ONE, 14(1), e0210416 Jan 24, JAN 2019, (SCI IF=2.4, rank=27/71=38.03% in Multidisciplinary Sciences, JCR 2019).

18. Wei-Hsiung Chang, Ching-Chang Lee (equally contribution with corresponding author), Yun-He Yen, Hsiu-Ling Chen, Oxidative damage in patients with benign prostatic hyperplasia and prostate, cancer co-exposed to phthalates and to trace elements, Environment International, 121, 1179-1184,Dec 2018. (SCI IF=7.943, rank=9/250=3.6% in Environmental Science, JCR 2018).

19. Chien-YingYan, Siang-Chen Wu, Ching-Chang Lee, Yang-hsinShih, Translocation of polybrominated diphenyl ethers from field-contaminated soils to an edible plant. Journal of hazardous materials, 351, 215-223, June 2018 (SCI IF=7.650, rank=12/250=4.8% in Environmental Sciences, JCR 2018).

20. Po-Chin Huang, Kai-Wei Liao, Jung-Wei Chang, Shiou-Hui Chan, Ching-Chang Lee, (corresponding author), Characterization of phthalates exposure and risk for cosmetics and perfume sales clerks. Environmental Pollution, 233, 577-587, Feb 2018. (SCI IF=5.714, rank=25/250=10% in Environmental Sciences, JCR 2018)

 

Conference Papers

1. Lan I, Wei-Hsiang Chang, Ching-Chang Lee. Risk Assessment and Management of Dietary Exposure to Phthalate Esters for Taiwanese, 2021 年（第35 屆）環境分析化學研討會，台灣桃園行政院環境保護署環境檢驗所，2021年6月29-30日。

2. Chia-Hui Chieh, Yu-Hsuan Liu, Wei-Hsiang Chang, Ching-Chang Lee. Exposure characteristics of indoor organophosphate flame retardants via multiple exposures routes in children, 2021 年TSIEQ研討會，台灣，國立成功大學，2021年6月3-4日。(學生論文競賽獎第二名)

3. Jyun-Yi Ciou, Wei-Hsiang Chang, Chien-Cheng Jung, Ching-Chang Lee. Investigating associations between building characteristics, PM2.5 and organophosphate flame retardants in Tainan households. TSIEQ 2021年亞洲室內環境品質、健康防疫與智慧生活研討會，台灣室內環境品質協會、國立成功大學，2021年6月3-4日。

4. Wan-Yu Luo, Wei-Hsiang Chang, Ching-Chang Lee. Long Term Exposure Assessment of Polychlorinated dibenzo-p-dioxins and dibenzofurans for Operation Workers of Municipal Waste Incinerators: 2008-2020. 2021年職業衛生暨職業醫學國際學術研討會，台灣臺北醫學大學，2021年4月23-25日。

5. Yu-Hsuan Liu, Wei-Hsiang Chang, Ching-Chang Lee. Occurrences and characterization of organophosphate flame retardants in indoor air and dust: a multi‐location households study. Indoor air 2020 Seoul, Korea, Nov 1-3, 2020.

6. Ya-Hsuan Tasi, Yu-Wen Chang, Wei-Hsiang Chang, Meng-Xing Wu, Zhen-Xiang You, Ching-Chang Lee. The effects of maternal exposure to thyroid disrupting substances on the growth and development of newborns, 2020年公共衛生聯合年會暨學術研討會，2020年10月17-18日。

7.Wei-Hsiang Chang, Hsiu-Ling Chen, Ching-Chang Lee. Sex hormones and oxidative stress promote the development of prostatic hyperplasia with phthalate exposures. 2020公衛聯合年會學術研討會，台灣，國立臺灣師範大學，2020年10月17-18日。

8.黃婉瑜(W.Y, Huang), 張偉翔(W.H, Chang), 李俊璋(C.C, Lee). Occurrence of Short Chain Chlorinated Paraffins in sediment and fish from Taiwan principal rivers and biota-sediment accumulation Factors, 2020 年（第34 屆）環境分析化學研討會，台灣桃園行政院環境保護署環境檢驗所，2020年8月26-27日。(榮獲2020年優良論文獎)

9.Ning-Syuan Hsu, Wei-Hsiang Chang, Ching-Chang Lee. Temporal/Spatial Profile and Sources Investigation of polybrominated diphenyl ethers in sediment from Taiwan principle rivers. 2020 環境分析化學研討會，台灣環境檢驗所，2020年8月26-27日。

10. Chia-Hui Chieh, Yu-Hsuan Liu, Wei-Hsiang Chang, Ching-Chang Lee. The investigation of indoor/outdoor airborne organophosphate flame retardants and the relationship between those distribution with environmental conditions in Taiwan households, 2020 年（第34 屆）環境分析化學研討會，台灣桃園行政院環境保護署環境檢驗所，2020年8月26-27日。

11. Ya-Hsuan Tasi, Wei-Hsiang Chang, Ching-Chang Lee. Regional Profile and Sources Explore of Nonylphenol and Bisphenol A in Sediments of Taiwan Principal Rivers, 2020 年（第34 屆）環境分析化學研討會，台灣桃園行政院環境保護署環境檢驗所，2020年8月26-27日。

12. 黃婉瑜(W.Y, Huang), 張偉翔(W.H, Chang), 李俊璋(C.C, Lee). The Occurrence of Perfluoroalkyl substances of Sediment and Fish in Principal River Environment around Taiwan, 2021 年（第35 屆）環境分析化學研討會，台灣桃園行政院環境保護署環境檢驗所，2020年6月29-30日。

13. Mei-Chen Cheng, Yu-Wen Chang, Wei-Hsiang Chang, Meng-Hsing Wu, Chen-Hsiang Yu, Ching-Chang Lee. Potential Sources of thyroid disrupting chemicals and its effects of the neonatal development. 2019公衛聯合年會學術研討會，台灣國立臺灣大學，2019年9月26-28日。

14. Ching-Chang Lee and Yi-Yun Wu. The Occurrence and Bioaccumulation of Short Chain Chlorinated Paraffins in Sediment and Fish in Principal Rivers around Taiwan. 39th International Symposium on Halogenated Persistent Organic Pollutants, Kyoto, Japan, August 25-30, 2019.

15. Jung-Wei Chang, Ching-Chang Lee, Wei-Hsiang Chang. Temporal trends and spatial distribution of PCDD/Fs and dioxin-like PCBs in Taiwan foodstuffs. 39th International Symposium on Halogenated Persistent Organic Pollutants, Kyoto, Japan, August 25-30, 2019.

16. Wei-Hsiang Chang and Ching-Chang Lee. Estimated daily intake and cumulative risk assessment of perchlorate via diverse foods for Taiwanese populations. 39th International Symposium on Halogenated Persistent Organic Pollutants, Kyoto, Japan, August 25-30, 2019.

17. Hsiu-Ling Chen and Ching-Chang Lee. Temporal and spatial trend of polychlorinated dibenzo-p-dioxins/dibenzofuran and dioxin like polychlorinated biphenyl levels in food from Taiwan markets during 2004 to 2012 and 2013 to 2018. 39th International Symposium on Halogenated Persistent Organic Pollutants, Kyoto, Japan, August 25-30, 2019.

18. Sze Ting Choi, Hsiu-Ling Chen, Wei-Hsiang Chang, Ching-Chang Lee. The investigation of dioxins and dioxin-like polychlorobiphenyls in food and exposure assessment in Taiwan air quality maintenance zones. 2019食品衛生檢驗科技研討會，台灣嘉義永在食安大樓，2019年8月21-22日

19. Ching-Chang Lee, Wei-Hsiang Chang and Guan-Liang Wu.    Occurrence and profiles of phthalates in processed food from Taiwan and their implications for human exposure. International Association for Food Protection 2019 Annual Meeting (IAFP 2019), Louisville, Kentucky, United States, July 21-24, 2019.

20. Wei-Hsiang Chang and Ching-Chang Lee. Estimated daily intake and cumulative risk assessment of perchlorate via diverse foods for Taiwanese populations. International Association for Food Protection 2019 Annual Meeting (IAFP 2019), Louisville, Kentucky, United States, July 21-24, 2019.

21. Hsiu-Ling Chen and Ching-Chang Lee. Risk assessment for non-dioxin like polychlorinated biphenyls exposure from food consumption in Taiwanese. International Association for Food Protection 2019 Annual Meeting (IAFP 2019), Louisville, Kentucky, United States, July 21-24, 2019.

22. Yi-Wen Huang, Wei-Hsiang Chang, Ching-Chang Lee. Temporal and Spatial Distribution of Nonylphenol and Bisphenol A in sediment from Taiwan principal rivers and influence factors. 第33屆環境分析化學研討會暨學會年會，台灣桃園行政院環境保護署環境檢驗所，2019年5月16-17日。

23. Yu-Hsuan Liu, Wei-Hsiang Chang, Ching-Chang Lee. 室內環境空氣、灰塵及皮膚擦拭樣品中有機磷耐燃劑分析方法開發研究。第33屆環境分析化學研討會暨學會年會，台灣桃園行政院環境保護署環境檢驗所，2019年5月16-17日。

24. Ching-Chang Lee and Yi-Yun Wu. The Occurrence and Bioaccumulation of Short Chain Chlorinated Paraffins in Sediment and Fish in Principal Rivers around Taiwan. 39th International Symposium on Halogenated Persistent Organic Pollutants, Kyoto, Japan, August 25-30, 2019.

25. Jung-Wei Chang, Ching-Chang Lee, Wei-Hsiang Chang. Temporal trends and spatial distribution of PCDD/Fs and dioxin-like PCBs in Taiwan foodstuffs. 39th International Symposium on Halogenated Persistent Organic Pollutants, Kyoto, Japan, August 25-30, 2019.

26. Wei-Hsiang Chang and Ching-Chang Lee. Estimated daily intake and cumulative risk assessment of perchlorate via diverse foods for Taiwanese populations. 39th International Symposium on Halogenated Persistent Organic Pollutants, Kyoto, Japan, August 25-30, 2019.

27. Hsiu-Ling Chen and Ching-Chang Lee. Temporal and spatial trend of polychlorinated dibenzo-p-dioxins/dibenzofuran and dioxin like polychlorinated biphenyl levels in food from Taiwan markets during 2004 to 2012 and 2013 to 2018. 39th International Symposium on Halogenated Persistent Organic Pollutants, Kyoto, Japan, August 25-30, 2019.

28. Ching-Chang Lee, Wei-Hsiang Chang and Guan-Liang Wu. Occurrence and profiles of phthalates in processed food from Taiwan and their implications for human exposure. International Association for Food Protection 2019 Annual Meeting (IAFP 2019), Louisville, Kentucky, United States, July 21-24, 2019.

29. Wei-Hsiang Chang and Ching-Chang Lee. Estimated daily intake and cumulative risk assessment of perchlorate via diverse foods for Taiwanese populations. International Association for Food Protection 2019 Annual Meeting (IAFP 2019), Louisville, Kentucky, United States, July 21-24, 2019.

30. Hsiu-Ling Chen and Ching-Chang Lee. Risk assessment for non-dioxin like polychlorinated biphenyls exposure from food consumption in Taiwanese. International Association for Food Protection 2019 Annual Meeting (IAFP 2019), Louisville, Kentucky, United States, July 21-24, 2019.

31. Yu-Wen Chang, Wei-Hsiang Chang, Yu-Ping Fu, Ching-Chang Lee. Study on Association between Prenatal Exposure to Perchlorate, Nitrate, and Thiocyanate with Fetus Development. 2019國際職業衛生研討會，台灣台南長榮大學，2019年3月7-8日。(榮獲張火炎教授紀念獎學金)

32. Ching-Chang Lee, The effects of phthalate metabolites on testicular function in male adult, 2019 2nd International Conference on Agriculture, Food and Biotechnology (ICAFB 2019), 新加坡2019年1月22-25日

33. 李俊璋，The Occurrence of Short Chain Chlorinated Paraffins in Sediment and Fish in Principal River Environment around Taiwan 台灣地區主要河川底泥及魚體中短鏈氯化石蠟流布研究，The 4th Cross-Strait Conference of Environmental Analytical Chemisty第四屆海峽兩岸環境分析化學學術研討會，中國大陸香港，2018年12月16-20日。

34. 李俊璋，環境因子對室內建材VOCs及HCHO逸散影響研究，2018中國環境科學學會科學技術年會，中國安徽合肥，2018年8月3-5日。

35. Ching-Chang Lee and Wei-Hsiang Chang. Occurrence of Perchlorate in Bottled water, Beverage and Tea from Taiwan Market by High Performance Liquid Chromatography–Tandem Mass Spectrometry. International Association for Food Protection 2018 Annual Meeting (IAFP 2018), Salt Lake City, Utah, United State, July 8-11, 2018.

36. Wei-Hsiang Chang, Hsiu-Ling Chen, Shou-Chun Liu, Ching Chang Lee. Background Monitoring of Nonylphenol and Bisphenol a Levels in Foods Around Taiwan and BPA Migrating Test from Packaging Materials of Coffee Products. International Association for Food Protection 2018 Annual Meeting (IAFP 2018), Salt Lake City, Utah, United State, July 8-11, 2018.

37. Hsiu-Ling Chen, Ching Chang Lee, Wei-Hsiang Chang. Integrated Risk Assessment of nonylphenol and bisphenol A through dietary intake in Taiwan population. International Association for Food Protection 2018 Annual Meeting (IAFP 2018), Salt Lake City, Utah, United State, July 8-11, 2018.

38. Yu-Ping Fu, Wei-Hsiang Chang, Meng-Hsing Wu, Horng-Yih Ou, Ching-Chang Lee. Urinary perchlorate and thiocyanate are associated with thyroid function in pregnant women. Conference of International Society for Environmental Epidemiology and International Society of Exposure Science－Asia Chapter 2018 (ISEE/ES AC 2018), Taipei, Taiwan, June 21-25, 2018.

39. 張毓文 (Y.W, Chang), 張偉翔 (W.H, Chang), 李俊璋(C.C, Lee). Polybrominated diphenyl ethers in sediment from Taiwan principal rivers: levels, spatial and seasonal distribution and influence factors, 2018 年（第32 屆）環境分析化學研討會，台灣桃園行政院環境保護署環境檢驗所，2018年5月3-4日。

40. 吳冠良(G.L, Wu),張偉翔(W.H, Chang),李俊璋(C.C, Lee). The investigation of the association between phthalate levels in foodstuffs with different packaging materials, 2018 年（第32 屆）環境分析化學研討會，台灣桃園行政院環境保護署環境檢驗所，2018年5月3-4日。

41. 陳珮瑄(P.H, Chen), 張偉翔(W.H, Chang), 李俊璋(C.C, Lee). Monitoring and exposure risk assessment of perchlorate in bottled water, tea and tea drinks, 2018 年（第32 屆）環境分析化學研討會，台灣桃園行政院環境保護署環境檢驗所，2018年5月3-4日。

42. Yi-Hsin Lin, Jung-Wei Chang, Wen-Che Hou, Meng-Han Lee, Ching-Chang Lee. The Association between Nanoparticles Exposure and Health Outcomes in Cosmetic Sales Clerk, 2018 國際職業衛生研討會暨第九屆海峽兩岸職業衛生學術交流會，台灣台中弘光大學，2018年3月7-9日。

 

 

Chapters in Book

 1.安心吃、放心用，權威環境毒物專家教你輕鬆打造無毒生活：毒雞蛋、毒澱粉、塑化劑……生活中隱藏著各種不能吃、不能用的秘密，環境毒物權威教你輕輕鬆鬆一次全破解！，平安文化，2017.10.16.